The Pancreatic Cancer Early Detection Laboratory
Research Studies

We are studying gene expression patterns of pancreatic cancers using microarray technology. We are also studying DNA methylation patterns looking for genes that are methylated in pancreatic cancer but not in normal cells.

We have put together a profile of genes that are methylated in pancreatic cancer. Some pancreatic cancers methylate a lot of genes; most appear to methylate only a few genes. We are currently directing our efforts to identify additional genes methylated in pancreatic cancer using novel techniques. We are also studying the role of telomerase in pancreatic cancer and its potential as a marker for early detection.